Her artistic journey, rooted in self-expression and discovery since childhood, blossomed into a career marked by profound talent and dedication. From early triumphs in art competitions, including the prestigious Art against AIDS competition, Nthabiseng's creativity found expression in the harmonious interplay of oil paint, charcoal, and acrylics on canvas. Notably, her current focus has expanded to include a passion for organic pigments sourced from plants and rocks, further enriching her artistic repertoire with a commitment to sustainability.

Her works, infused with a deep appreciation for nature, African spirituality, and the cosmos, convey powerful messages and captivate viewers with intricate small-scale artworks. Honored with a Prince Claus Seed award in 2021, Nthabiseng stands among the world's 100 artists recognized for using art and sound to educate and heal communities